Vincent Bessonneau, PhD
Dr. Vincent Bessonneau is a research scientist with expertise in environmental health and metabolomics. His research centers on the use of the exposome concept (i.e. the totality of environmental exposures that an individual experiences in a lifetime) to identify adverse health outcomes risk biomarkers, and provide new insights into the etiology and biological mechanisms involved and associated with environmental exposures.
His research on metabolomics is being applied to identify previously unknown chemicals exposures that are higher among women firefighters and nurses, compared to office workers, and investigate their associations with biomarkers of breast cancer and early effects on metabolism
Prior to joining Silent Spring Institute in September 2016, Dr. Bessonneau worked as a Postdoctoral Fellow in the Department of Chemistry at the University of Waterloo in Canada, where he developed untargeted metabolomics methods to measure small molecules in biological specimens. He also investigated the use of saliva for non-invasive and repeated monitoring of the exposome to reduce exposure-measurement errors in exposome-wide association studies.
Dr. Bessonneau earned his PhD in Biology and Health Sciences at the École des Hautes Études en Santé Publique (EHESP School of Public Health) in France, where he developed new analytical methods and statistical approaches for better characterization of human exposure to volatile organic compounds.
Publications & Presentations
Su, Y., J. Santucci-Pereira, N.M. Dang, J. Kanefsky, V. Rahulkannan, M. Hillegass, S. Joshi, H. Gurdogan, Z. Chen, V. Bessonneau, R. Rudel, J. Ser-Dolansky, S.S. Schneider, J. Russo. 2022. Effects of Pubertal Exposure to Butyl Benzyl Phthalate, Perfluorooctanoic Acid, and Zeranol on Mammary Gland Development and Tumorigenesis in Rats. International Journal of Molecular Sciences. 23(3):1398. https://doi.org/10.3390/ijms23031398
Clarity, C., J. Trowbridge, R. Gerona, K. Ona, M. McMaster, V. Bessonneau, R. Rudel, H. Buren and R. Morello-Frosch. 2021. Associations between polyfluoroalkyl substance and organophosphate flame retardant exposures and telomere length in a cohort of women firefighters and office workers in San Francisco. Environmental Health. doi.org/10.1186/s12940-021-00778-z
Bessonneau, V., R.R. Gerona, J. Trowbridge, R. Grashow, T. Lin, H. Buren, R. Morello-Frosch, R.A. Rudel. 2021. Gaussian graphical modeling of the serum exposome and metabolome reveals interactions between environmental chemicals and endogenous metabolites. Scientific Reports. 11: 7607. doi.org/10.1038/s41598-021-87070-9
Trowbridge, J., R.R. Gerona, T. Lin, R.A. Rudel, V. Bessonneau, H. Buren, R. Morello-Frosch. 2020. Exposure to Perfluoroalkyl Substances in a Cohort of Women Firefighters and Office Workers in San Francisco. Environmental Science & Technology. doi.org/10.1021/acs.est.9b05490
Grashow, R., V. Bessonneau, R.R. Gerona, A. Wang, J. Trowbridge, T. Lin, H. Buren, R.A. Rudel, R. Morello-Frosch. 2020. Integrating exposure knowledge and serum suspect screening as a new approach to biomonitoring: An application in firefighters and office workers. Environmental Science & Technology. doi.org/10.1021/acs.est.9b04579
Bessonneau, V., and R.A. Rudel. 2020. Mapping the Human Exposome to Uncover the Causes of Breast Cancer. International Journal of Environmental Research and Public Health. 17(1): 189. doi.org/10.3390/ijerph17010189