Predicting Chemical Hazards

Kay, J.E., J.G. Brody, M. Schwarzman, R.A. Rudel. 2024. Application of the Key Characteristics framework to identify potential breast carcinogens using publicly available in vivo, in vitro, and in silico data. Environmental Health Perspectives. https://doi.org/10.1289/EHP13233

Borrel, A., Rudel, R. 2022. Cheminformatics analysis of chemicals that increase estrogen and progesterone synthesis for a breast cancer hazard assessment. Scientific Reports. 12, 20647. doi: 10.1038/s41598-022-24889-w

Kay J.E., B. Cardona, R.A. Rudel, L.N. Vandenberg, A.M. Soto, S. Christiansen, L.S. Birnbaum, S.E. Fenton. 2022. Chemical Effects on Breast Development, Function, and Cancer Risk: Existing Knowledge and New Opportunities. Current Environmental Health Reports. 9, 535–562. doi: 10.1007/s40572-022-00376-2.

Rudel, R.A., B. Cardona, A. Borrel, J.E. Kay. 2022. Response to “Comment on ‘Application of an in Vitro Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors’”. Environmental Health Perspectives. 130(5):58003. doi: 10.1289/EHP11400

Cardona, B. and R.A. Rudel. 2021. Application of an in vitro assay to identify chemicals that increase estradiol and progesterone synthesis and are potential breast cancer risk factors. Environmental Health Perspectives. 129(7):77003. doi: 10.1289/EHP8608

Bessonneau, V., and R.A. Rudel. 2020. Mapping the Human Exposome to Uncover the Causes of Breast Cancer. International Journal of Environmental Research and Public Health. 17(1): 189. doi: 10.3390/ijerph17010189

Grashow, R.G., V.Y. De La Rosa, S.M. Watford, J.M. Ackerman, R.A. Rudel. 2018. BCScreen: A gene panel to test for breast carcinogenesis in chemical safety screening. Computational Toxicology. 5:16-24. doi: 10.1016/j.comtox.2017.11.003

Rudel, R., Kripke M.L., and Yaswen, P. Predicting Toxicity: Silent Spring Institute's High-throughput Screens for Chemicals Related to Breast Cancer. Collaborative on Health and the Environment. November 12, 2015.

Pan, S., C. Yuan, A. Tagmount, R.A. Rudel, J.M. Ackerman, P. Yaswen, C.D. Vulpe, D.C. Leitman. 2015. Parabens and Human Epidermal Growth Factor Receptor Ligands Cross-Talk in Breast Cancer Cells. Environmental Health Perspectives, 124(5):563-569. doi:10.1289/ehp.1409200

Schwarzman M.R., J.M. Ackerman, S.H. Dairkee, S.E. Fenton, D. Johnson, K.M. Navarro, G. Osborne, R.A. Rudel, G.M. Solomon, L. Zeise, S. Janssen. 2015. Screening for chemical contributions to breast cancer risk:  A case study for chemical safety evaluation. Environmental Health Perspectives, 123(12):1255-1264. doi:10.1289/ehp.1408337